Joint Solution's Collagen and HA and their role in Joint Health

There are 14 different types of collagen found in the body but only type II is the most abundant in the joint matrix. Joint Solution with Collagen and HA's collagen and its constituents can have a powerful impact on joints and conditions associated with abnormal joint function. One study published in 2000 entitled "Role of Collagen Hydrolysate in Bone and Joint Disease" reviews how collagen can be a powerful tool in helping with osteoarthritis and even osteoporosis. The researchers of this study state "its high level of safety (hydrolyzed collagen) makes it attractive as an agent for long-term use in these chronic disorders." A placebo-controlled joint efficacy study directed by Dr. Eric Sheldon, a clinical research investigator at Miami Research Associates, examined sixteen men and women with OA who received the Collagen Type II, Hyaluronic Acid and Chondroitin supplement found in Joint Solution with Collagen and HA for an eight-week period. Sheldon said the data reveals that daily consumption of the supplement led to clinically meaningful improvements that were significantly superior to the group receiving placebo supplements. "This preliminary study suggests that [this supplement matrix] has promise in the management of chronic OA symptoms," said Sheldon, a rheumatologist and voluntary rheumatology instructor at the University of Miami School of Medicine. "We used a symptom assessment tool that is used routinely in OA drug studies and the results were encouraging."

The components of Joint Solution with Collagen and HA's collagen type II, chondroitin sulfate and hyaluronic acid can support proteoglycans and glycosaminoglycans (GAG's) in the joint matrix thereby increasing synovial (joint) fluid and supporting cartilage synthesis in the joints. This can enhance a joint's shock absorption capabilities as well as lower the chance for deterioration.

HA specifically is a key nutrient in joint health. In a review by Moskowitz from Case Western Reserve University entitled "Hyaluronic acid supplementation" and published in 2000, he states that "Hyaluronan preparations have been shown to decrease pain and increase function in patients with osteoarthritis of the knee."

HA seems to work by restoration of more normal synovial fluid with improved viscoelasticity, effects on cartilage biosynthesis and degradation, anti-inflammatory effects, and direct analgesic effects.